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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX1 All Species: 18.18
Human Site: S1143 Identified Species: 25
UniProt: O43933 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43933 NP_000457.1 1283 142867 S1143 S E L G N G T S S D L S S Q C
Chimpanzee Pan troglodytes XP_519198 1283 142803 S1143 S E L G N G T S S D L S S Q C
Rhesus Macaque Macaca mulatta XP_001101055 1278 142022 S1138 S E L G N G T S S D L S S Q C
Dog Lupus familis XP_532459 1267 140567 S1127 S E L G N G T S S D L S P Q C
Cat Felis silvestris
Mouse Mus musculus Q5BL07 1284 141409 P1144 S E L G N G T P S D L S S H C
Rat Rattus norvegicus P46462 806 89330 A667 N L R K S P V A K D V D L E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520628 1178 126535 F1037 F S V Y R L Y F G S S Y E S E
Chicken Gallus gallus XP_418655 1290 143066 S1151 E L G N G T P S E L S S L C L
Frog Xenopus laevis P23787 805 89193 V666 A N L R K S P V A K D V D V D
Zebra Danio Brachydanio rerio Q7ZU99 806 89405 S667 N L R K S P I S K D V D L D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841 P662 K A N L R K S P L A K E V D L
Honey Bee Apis mellifera XP_397107 1069 120490 T930 C K R Q K V D T T G L D L K E
Nematode Worm Caenorhab. elegans P54812 810 89622 L671 A S L R K T P L S A D L D L N
Sea Urchin Strong. purpuratus XP_797089 1508 166130 S1368 T P S P P E G S V F D T T M T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCN8 815 90322 L676 P V A K D V D L R A L A K Y T
Baker's Yeast Sacchar. cerevisiae P24004 1043 117258 K904 D L K L I A E K T A G F S G A
Red Bread Mold Neurospora crassa Q7SGP2 1381 148356 N1232 D T K I R E L N A A A G P E G
Conservation
Percent
Protein Identity: 100 99.6 92.8 86.4 N.A. 82 23.3 N.A. 52.4 62.4 22.9 22.8 N.A. 23.6 27.6 22.1 35.2
Protein Similarity: 100 100 94.9 92 N.A. 89.5 39.2 N.A. 66 77.6 38.6 39 N.A. 37.6 46.7 38.4 53.2
P-Site Identity: 100 100 100 93.3 N.A. 86.6 6.6 N.A. 0 13.3 6.6 13.3 N.A. 0 6.6 13.3 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 40 N.A. 6.6 13.3 20 33.3 N.A. 6.6 33.3 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23.5 25.7 21.4
Protein Similarity: N.A. N.A. N.A. 38.5 45.2 40.9
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 0
P-Site Similarity: N.A. N.A. N.A. 20 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 6 6 0 0 6 0 6 12 30 6 6 0 0 6 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 0 0 0 6 30 % C
% Asp: 12 0 0 0 6 0 12 0 0 42 18 18 12 12 6 % D
% Glu: 6 30 0 0 0 12 6 0 6 0 0 6 6 12 12 % E
% Phe: 6 0 0 0 0 0 0 6 0 6 0 6 0 0 12 % F
% Gly: 0 0 6 30 6 30 6 0 6 6 6 6 0 6 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % H
% Ile: 0 0 0 6 6 0 6 0 0 0 0 0 0 0 0 % I
% Lys: 6 6 12 18 18 6 0 6 12 6 6 0 6 6 0 % K
% Leu: 0 24 42 12 0 6 6 12 6 6 42 6 24 6 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % M
% Asn: 12 6 6 6 30 0 0 6 0 0 0 0 0 0 6 % N
% Pro: 6 6 0 6 6 12 18 12 0 0 0 0 12 0 0 % P
% Gln: 0 0 0 6 0 0 0 0 0 0 0 0 0 24 0 % Q
% Arg: 0 0 18 12 18 0 0 0 6 0 0 0 0 0 0 % R
% Ser: 30 12 6 0 12 6 6 42 36 6 12 36 30 6 0 % S
% Thr: 6 6 0 0 0 12 30 6 12 0 0 6 6 0 12 % T
% Val: 0 6 6 0 0 12 6 6 6 0 12 6 6 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 6 0 0 0 0 6 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _